Further information
Significance: Amiodarone is an excellent antiarrhythmic medication; however, it has numerous systemic and ocular adverse effects
Call your healthcare provider if you develop symptoms of nerve problems, including: a feeling of "pins and needles" or numbness in your hands, legs, or feet, muscle weakness, uncontrolled movements, poor coordination, or trouble walking
Loading dose: 800 to 1600 mg orally per day for 1 to 3 weeks (occasionally longer) until adequate arrhythmia control is achieved or if side effects become prominent, then switch to adjustment dose
In contrast to the phototoxic reactions, which do not depend on the skin type, hyperpigmentation usually occurs in patients with skin type I phototype []
Drug induced hypothyroidism, amiodarone; Hyperthyroidism due to amiodarone; Hypothyroidism due to amiodarone; Thyroiditis due to amiodarone; ICD-10-CM T46
Your skin may continue to be sensitive to sunlight for several months after treatment is stopped
As an analog of amiodarone, dronedarone is chemically similar to amiodarone
Its efficacy has been challenged by its ubiquitous organ toxicity resulting in nearly 50% of long-term users discontinuing the drug
Intrinsic amiodarone-related drug effects
Long-term administration of amiodarone decreased IK to 55% (n510) in control rabbits and altered the relative density The effect of antiarrhythmic drugs, beta-blockers and calcium channel blockers on rhythm, conduction and ECG waveforms
However, by the choice of the drug company (probably to avoid the unusually tough American regulatory